Development of a rep-inducible, BBTV-based expression system in banana



  • Authors : Bolton, C.L.

  • Document type : Thesis

  • Diploma : PhD Thesis (Bachelor on Applied Science)

  • Year of publication : 2009

  • Publisher(s) : Queensland University of Technology

  • Place of publication : Brisbane (AUS)

  • ISBN : 978-80-227-2903-1

  • Pages : 217

  • Language(s) : English

  • Abstract : Banana bunchy top is regarded as the most important viral disease of banana, causing significant yield losses worldwide. The disease is caused by Banana bunchy top virus (BBTV), which is a circular ssDNA virus belonging to the genus Babuvirus in the family Nanoviridae. There are currently few effective control strategies for this and other ssDNA viruses. "In Plant Activation" (InPAct) is a novel technology being developed at QUT for ssDNA virus-activated suicide gene expression. The technology exploits the rolling circle replication mechanism of ssDNA viruses and is based on a unique "split" gene design such that suicide gene expression is only activated in the presence of the viral Rep. This PhD project aimed to develop a BBTV-based InPAct system as a suicide gene strategy to control BBTV... (Author's abstract).

  • Keywords : BANANA BUNCHY TOP VIRUS; DISEASE CONTROL; GENETIC MARKERS; GENETIC CONTROL; GENETIC MAPS; GENE EXPRESSION

  • Open access : Yes

  • Document on publisher's site : open View article on publisher's site

  • Musalit document ID : IN090449


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