Abacá bunchy top virus, a new member of the genus Babuvirus (family Nanoviridae)

• Authors : Sharman, M.; Thomas, J.E.; Skabo, S.; Holton, T.A.


• Document type : Journal article


• Year of publication : 2008


• Journal title : Archives of Virology


• Volume (number) : 153 (1)




• Pages : 135-147


• Peer-reviewed : Yes


• ISSN : 0304-8608; 1432-8798


• Language(s) : English


• Abstract : Two isolates of a novel babuvirus causing ''bunchy top'' symptoms were characterised, one from abaca¦ (Musa textilis) from the Philippines and one from banana (Musa sp.) from Sarawak (Malaysia). The name abaca¦ bunchy top virus (ABTV) is proposed. Both isolates have a genome of six circular DNA components, each ca. 1.0-1.1 kb, analogous to those of isolates of Banana bunchy top virus (BBTV). However, unlike BBTV, both ABTV isolates lack an internal ORF in DNA-R, and the ORF in DNAU3 found in some BBTV isolates is also absent. In all phylogenetic analyses of nanovirid isolates, ABTV and BBTV fall in the same clade, but on separate branches. However, ABTVand BBTV isolates shared only 79-81 percent amino acid sequence identity for the putative coat protein and 54-76 percent overall nucleotide sequence identity across all components. Stem-loop and major common regions were present in ABTV, but there was less than 60 percent identity with the major common region of BBTV. ABTV and BBTV were also shown to be serologically distinct, with only two out of ten BBTV-specific monoclonal antibodies reacting with ABTV. The two ABTV isolates may represent distinct strains of the species as they are less closely related to each other than are isolates of the two geographic subgroups (Asian and South Pacific) of BBTV.


• Keywords : BANANA BUNCHY TOP VIRUS; GENOMES; MUSA TEXTILIS; ABACA; PHILIPPINES


• Open access : No


• Document on publisher's site : View article on publisher's site


• Musalit document ID : IN080501

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